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Pyrrole inhibitors of ERK protein kinase
Nicholson JR
Heart Rhythm
targets mutant FLT3 and is currently in late-stage clinical trials
Lersivirine (UK-453061) Asn-PAB-PNP Pyrrole inhibitors of ERK proteinLersivirine (UK 453061) is a potent and selective inhibitor of nonnucleoside reverse transcriptase (NNRTI) with IC50 of 0. 119 M. Product information CAS Number: 473921 12 9 Molecular Weight: 310. 35 Formula: C17H18N4O2 Chemical Name: 5 ((3,5 diethyl 1 (2 hydroxyethyl) 1H pyrazol 4 yl)oxy)isophthalonitrile Smiles: CCC1=NN(CCO)C(CC)=C1OC1C=C(C=C(C=1)C#N)C#N InChiKey: MCPUZZJBAHRIPO UHFFFAOYSA N InChi: InChI=1S C17H18N4O2 c1 3 15 17(16(4 2)21(20 15)5 6
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