In general, there are four rarities in MTG: common, uncommon, rare, and mythic rare
Lotho, Corrupt Shirriff wont get your Exquisite Blood combos going, but you assemble a deck that plays with lifegain and life loss
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It's strong everywhere, but it has enhanced value in archetypes that care about counters generally, +1/+1 counters specifically, proliferate tricks for multicolor brews looking to add loyalty counters for their planeswalkers, four and five-color decks, Commanders with evasion, Commanders with a power that, when increased by 1 get a faster kill, Equipment, Aura, and Voltron decks looking to get in kills with their Commander, and loads more