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and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes
PF-04457845 inhibits FAAH by a covalent
Chemical Name: N-[3-(6-{[4-(1
Smiles: O=C(C1C=CC(F)=CC=1)N1C[C@H](CCC1)C1=NC(=NO1)C1C=CC(F)=CC=1
CZC-25146 Hydrochloride 64 2HCl and causes morphological changes (1CZC 25146 is a potent and selective LRRK2 inhibitor. Leucine rich repeat kinase 2 (LRRK2) mutations are the most important cause of familial Parkinson's disease. CZC 25146 prevents mutant LRRK2 induced injury of cultured rodent and human neurons with mid nanomolar potency. Product information CAS Number: 1330003 04 7 Molecular Weight: 525. 00 Formula: C22H26ClFN6O4S Chemical Name: N {2 [(5 fluoro 2 {[2 methoxy 4 (morpholin 4 yl)phenyl]amino}pyrimidin