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Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 Mad2 Inhibitor-1 (M2I-1): A Small

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Description

Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint

Formula: C27H26N4O2

Savitski MM

ML213 is an activator of Kv72 KCNQ2 and Kv74 KCNQ4 channels with EC50s of 230 and 510 nM respectively

Dolutegravir - CAS# 1051375-16-6 Catalog No.:M11383-2 Mad2 Inhibitor-1 (M2I-1): A SmallDolutegravir, also known as GSK1349572, is a potent inhibitor of HIV integrase with an IC50 value of 2. 7 nM for HIV 1 integrase catalyzed strand transfer in vitro. 1 It inhibits HIV 1 viral replication (EC50 = 0. 51 nM) in peripheral blood mononuclear cells (PBMCs). Dolutegravir (DTG) is an antiretroviral medication used, together with other medication, to treat HIV AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV

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